Organic phosphoric acids and derivatives
Apexbio Technology LLC KN-92 phosphate 1135280-28-2 10mg
KN-92 phosphate is a small-molecule analog of the Ca2 /calmodulin-dependent kinase II (CaMKII) inhibitor KN-93 It is designed as an inactive control compound to distinguish CaMKII-specific effects in experimental settings KN-92 phosphate does not inhibit CaMKII activity and thus serves as a negative control for CaMKII inhibition studies Additionally KN-92 phosphate blocks certain voltage-gated potassium (Kv) channels such as Kv1 2 and Kv1 5 reducing steady-state current amplitudes upon depolarization Based on these pharmacological properties KN-92 phosphate holds research potential in investigating mechanisms underlying CaMKII-related signaling pathways and Kv channel functions
eMolecules 54-47-7 | Pyridoxal phosphate | Oakwood Chemical | MFCD00006333 | 247.143 | C8H10NO6P | 95.000 | Cc1ncc(COP(O)(O)=O)c(C=O)c1O | 25g | 537692511
Pyridoxal phosphate | Oakwood Chemical | 54-47-7 | MFCD00006333 | 247.143 | C8H10NO6P | 95.000 | Cc1ncc(COP(O)(O)=O)c(C=O)c1O | 25g | 537692511
eMolecules 54-47-7 | Pyridoxal phosphate | Oakwood Chemical | MFCD00006333 | 247.143 | C8H10NO6P | 95.000 | Cc1ncc(COP(O)(O)=O)c(C=O)c1O | 500g | 537692513
Pyridoxal phosphate | Oakwood Chemical | 54-47-7 | MFCD00006333 | 247.143 | C8H10NO6P | 95.000 | Cc1ncc(COP(O)(O)=O)c(C=O)c1O | 500g | 537692513
Medchemexpress LLC Carvedilol phosphate hemihydrate | 610309-89-2 | 99.9% | C24H26N2O4.H3PO4.1/2H2O | 1 G
Carvedilol phosphate hemihydrate is a non-selective β/α-1 blocker and a multiple action antihypertensive agent. It has potential applications in angina and congestive heart failure. This compound also acts as an autophagy inducer and inhibits the NLRP3 inflammasome.
- Non-selective β/α-1 blocker
- Inhibits lipid peroxidation with an IC50 of 5 μM
- Multiple action antihypertensive agent
- Potential applications in angina and congestive heart failure
- Autophagy inducer
- Inhibits NLRP3 inflammasome
- Inhibits superoxide generation by activated human neutrophils in vitro with an IC50 of 28 μM
- Scavenges oxygen free radicals in a cell-free system with an IC50 of 25 μM
Research Products International Corp p-Nitrophenyl-a-L-arabinofuranoside, 25 MG
- CAS Number: 6892-58-6
- Molecular Formula: C11H13NO7
- Molecular Weight: 271.22
Medchemexpress LLC Iproniazid phosphate | 305-33-9 | 99.9% | 1 ML
Iproniazid phosphate is an orally active, irreversible, non-selective monoamine oxidase (MAO) inhibitor. It inhibits MAO activity and enhances Rotenone-induced apoptosis. Iproniazid phosphate modulates neurotransmitter levels, affects neuronal function, induces hepatic necrosis, and interferes with the endocrine system. It can be used in the research of depression, Parkinson's disease, and hepatotoxicity.
- Non-selective, irreversible monoamine oxidase (MAO) inhibitor
- Hydrazine class inhibitor
- Has antidepressive activity
- Modulates neurotransmitter levels
- Affects neuronal function
- Induces hepatic necrosis
- Interferes with the endocrine system
- Used in research of depression, Parkinson's disease, and hepatotoxicity
Medchemexpress LLC Pyridoxal phosphate | 54-47-7 | 99.95% | 500 UG
Pyridoxal phosphate is the active form of vitamin B6, acts as an inhibitor of reverse transcriptases, and is used for the treatment of tardive dyskinesia. This product is for research use only.
- Severely inhibits DNA Polymerase and RNase H, leading to an immediate reduction in DNA synthesis.
- Conjugation to pyridoxal phosphate fully inhibits NEIL2.
- Activates the ERK/c-Jun signaling pathway and promotes IGFBP1 protein expression in HepG2 cells.
- Inhibits the proliferation of cancer cells SK-OV-3 and OVCAR-3.
- Alleviates Aβ25-35-induced spatial and long-term memory impairment in mouse models.
- Inhibits the formation of advanced glycation end-products (AGEs) and prevents the progression of diabetic nephropathy.
Medchemexpress LLC Pyridoxal 5'-phosphate (monohydrate) | 41468-25-1 | 98.0% | 265.16 | 1 G
Pyridoxal 5'-phosphate (monohydrate) | 41468-25-1 | 98.0% | 265.16 | 1 G
Medchemexpress LLC sn-Glycerol 3-phosphate | 17989-41-2 | 98.0% | 172.07 | 1 MG
sn-Glycerol 3-phosphate is a crucial intermediate in glycolysis and lipid metabolism. It is generated from dihydroxyacetone phosphate (DHAP) by the cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH). Glyceroneogenesis is a significant supplier of sn-Glycerol 3-phosphate for lipid metabolism.
- Intermediate in glycolysis and lipid metabolism.
- Generated from dihydroxyacetone phosphate by cytosolic GPDH.
- Passes through the permeable mitochondrial outer membrane.
- Reoxidized to DHAP by mitochondrial FAD-GPDH.
- DHAP subsequently channeled back to the cytosolic compartment.
Medchemexpress LLC Sn-Glycerol 3-phosphate | 17989-41-2 | >=98.0% | 172.07 | 1 ML
sn-Glycerol 3-phosphate is a crucial intermediate involved in glycolysis and lipid metabolism. It is produced by the cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) from dihydroxyacetone phosphate (DHAP) and is also a key supplier for lipid metabolism through glyceroneogenesis.
- Important intermediate in glycolysis and lipid metabolism.
- Generated from dihydroxyacetone phosphate (DHAP) by cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH).
- Plays a role in glyceroneogenesis as a supplier for lipid metabolism.
- Stable salt forms, such as sn-Glycerol 3-phosphate lithium, retain similar biological activity.
eMolecules 838-85-7 | Diphenyl hydrogen phosphate | Synthonix - Stock250.190 | C12H11O4P | 98.000 | OP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 459642385
Diphenyl hydrogen phosphate | Synthonix - Stock | 838-85-7250.190 | C12H11O4P | 98.000 | OP(=O)(Oc1ccccc1)Oc1ccccc1 | 5g | 459642385
Medchemexpress LLC sn-Glycerol 3-phosphate lithium | 99.9% | 183.94 | 25 MG
sn-Glycerol 3-phosphate lithium is a crucial intermediate in glycolysis and lipid metabolism. The cytosolic sn-Glycerol 3-phosphate dehydrogenase (GPDH) uses NADH to produce it from dihydroxyacetone phosphate (DHAP). Glyceroneogenesis is a significant source for lipid metabolism. It is intended for research use only and not for sale to patients.
- Endogenous metabolite
- Important intermediate in glycolysis and lipid metabolism
- Cytosolic GPDH consumes NADH to generate it from DHAP
- Glyceroneogenesis is an important supplier for lipid metabolism